Pigmented progressive purpuric dermatosis - 色素性紫癜性皮病
https://en.wikipedia.org/wiki/Pigmented_purpuric_dermatosis
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Schamberg disease ― 一名 26 歲男性,腿部有一塊無症狀色素沉著和毛細血管擴張。
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References
Pigmented Purpuric Dermatoses: A Complete Narrative Review 34070260 NIH
Pigmented purpuric dermatoses (PPD) 是一組皮膚狀況,其特徵是由於毛細血管發炎導致皮下小面積出血。 PPD 通常以紅色到紫色的斑點開始,隨後隨著含鐵血黃素的重新吸收而變成金棕色。
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg Disease 32809367 NIH
Schamberg disease 是最常見的 pigmented purpuric dermatoses (PPDs) 類型,這是一種慢性皮膚病,其特徵是紅色或紫色小斑點,以及皮膚顏色增加(棕色、紅色或黃色斑塊)。 PPD 分為五種: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis 。 Schamberg disease (SD) 也稱為 progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura 。它主要影響男性,通常出現在小腿上,但也可能出現在大腿、臀部、軀幹或手臂上。
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis 26273156 NIH
分析了 113 名 PPD 患者的信息,其中 38 名患者在本研究中接受了皮膚活檢。最常見的臨床類型是 Schamberg 病 (60. 5%) 。除產後憂鬱症外,其他疾病還包括高血壓(15. 8%)、糖尿病(10. 5%)等。用藥史顯示他汀類藥物(13. 2%)、β受體阻斷劑(10. 5%)等。與產後憂鬱症相關的可能因素包括近期上呼吸道感染(5. 3%)、長時間站立導致立位壓高(2. 6%)和劇烈運動(2. 6%)。 36 名患者 (94. 7%) 接受了治療 - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy 。
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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